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Table 2 Linkage of a QHCl QTL to D6Mit13 on chromosome 6.

From: Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice

   

1 mM qhcl

3 mM qhcl

Chr

Marker

Position (Mb)

LRS

% Var

p

Add

LRS

% Var

p

Add

6

D6Mit150

116.543

12.1

51

0.0005

0.16

11.9

50

0.00057

0.08

6

D6Mit254

125.974

11.4

49

0.00075

0.16

11.1

48

0.00087

0.07

6

D6Mit194

126.895

11.4

49

0.00075

0.16

11.1

48

0.00087

0.07

6

D6Mit61

129.173

nd

nd

nd

nd

nd

nd

nd

nd

6

D6Mit13

132.672

21.0

71

0.000001*

0.19

17.9

65

0.00002

0.09

6

D6Mit374

134.172

14.0

56

0.00018

0.17

14.3

57

0.00015

0.08

6

D6Mit301

136.104

14.0

56

0.00018

0.17

14.3

57

0.00015

0.08

6

SO6Gnf140.060

140.060

11.9

50

0.00056

0.17

12.7

53

0.00037

0.08

8

SO8Gnf046.785

46.785

13.4

55

0.00025

0.17

12.2

51

0.00047

0.08

  1. Markers are listed from proximal (D6Mit150) to distal (SO8Gnf046.785), with physical position indicated in Mb. The physical position of D6Mit194 (italics) should be considered tentative. The LRS (likelihood ratio statistic) is listed for each locus, signifying the level of association of the trait (QHCl taste sensitivity) with each locus. Variance (Var) refers to the amount of the total trait variance explained by a QTL at this locus, as a percentage. Additive regression coefficients (Add) are listed for each association; in each case the coefficient is positive, indicating that D2 alleles increase the trait value (i.e. higher lick ratios). In simple marker regression analysis, all of these loci are associated with QHCl sensitivity at p < 0.001; only the association of sensitivity to 1 mM QHCl with D6Mit13 reaches genome-wide significance (asterisk).
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BMC Genomic Data

ISSN: 2730-6844

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