Table 1 Contributions toward association tests from the GWAS group
From: Methods and results from the genome-wide association group at GAW20
Goal | Reference | Phenotype | Data type | Statistic type |
|---|---|---|---|---|
A gene-level association test | Park et al. [6] | Single quantitative trait | Family real GOLDN genetic data | Combined score based test |
A haplotype based association test | Zhou et al. [8] | Single binary trait | Case-control and trio GOLDN real genetic data | Bayes factor |
A gene-environment interaction test | Gao et al. [7] | Single quantitative or binary trait | GAW20 Case-control simulated genetic data | Score based test |
Joint association analysis of single SNPs and DNA methylation markers | Shen et al. [10] | Single quantitative trait | Family real GOLDN genetic and methylation data | Score based test |
Jointly analyzing multiple phenotypes | Deng et al. [9] | Multiple quantitative traits | Family real GOLDN genetic data | Pedigree-based USAT (pUSAT) |