Fig. 3

Selection of diagnostic biomarkers and identification of key genes. A Select POAG biomarkers by random forest. B Select POAG biomarkers by SVM. C Key genes extracted from the random forest and SVM methods. SVM, support vector machine; Keratin 14, KRT14; Hemoglobin subunit beta, HBB; Acyl-CoA Oxidase 2, ACOX2; Hephaestin, HEPH; and Keratin 13, KRT13