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Table 3 Prediction of the stability for the five deleterious nsSNPs using I-Mutant v2.0 and MUPro servers

From: Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses

ID of SNPs

SUB

I-Mutant v2.0

MUPro

Prediction

RI

DDG

Prediction

Score

rs1449638481

S53Y

increase

3

0.43

decrease

-1.3227

rs1041942016

E100K

decrease

9

-2.61

decrease

1.2026

rs1478935996

D128Y

decrease

2

1.06

decrease

-0.2066

rs1681958816

F228S

decrease

8

-2.43

decrease

-1.1535

rs1199067235

T240I

decrease

5

0.09

decrease

0.0428

  1. DDG; free energy change value, SUB; amino acid substitution, RI; Relatability index