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Table 4 Conservation profile of the five most deleterious nsSNPs using ConSurf server

From: Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses

SNPs ID

Residue and position

Conservation color

Prediction

rs1449638481

S53

9

Highly conserved and buried (s)

rs1041942016

E100

9

Highly conserved and exposed (f)

rs1478935996

D128

9

Highly conserved and exposed (f)

rs1681958816

F228

9

Highly conserved and buried (s)

rs1199067235

T240

9

Highly conserved and exposed (f)

  1. (f); predicted to be functional residue, (s); predicted to be structural residue