Table 2 Comparison of p-values of lncRNA-miRNA-mRNA triplets, prognostic lncRNA-mRNA pairs obtained from our previous study [28], and each RNA involved in the triplets from the Cox proportional hazards model
Cancer | Group | lncRNA-miRNA-mRNA triplet | p-value from the Cox model | ||||
|---|---|---|---|---|---|---|---|
triplet | lncRNA-mRNA pair | lncRNA | mRNA | miRNA | |||
BRCA | 1 | DIRC3_hsa-mir-183_PTP4A2 | 3.53e-8 | 2.21e-1 | 2.26e-1 | 5.37e-1 | 2.26e-1 |
HCG9_hsa-mir-192_PHTF2 | 1.79e-6 | 6.14e-1 | 4.95e-1 | 8.77e-1 | 4.95e-1 | ||
GDNF-AS1_hsa-mir-424_LRRFIP2 | 5.54e-6 | 3.45e-1 | 2.85e-1 | 3.92e-1 | 2.85e-1 | ||
2 | DIRC3_hsa-mir-191_SLC16A2 | 1.41e-9 | 3.35e-4 | 7.14e-1 | 2.86e-1 | 7.14e-1 | |
DIRC3_hsa-mir-191_TMC7 | 1.13e-8 | 3.06e-3 | 5.30e-1 | 3.96e-2 | 5.30e-1 | ||
DIRC3_hsa-mir-424_RTN4 | 4.40e-8 | 2.85e-2 | 2.03e-1 | 4.30e-1 | 2.03e-1 | ||
LIHC | 1 | HAS2-AS1_hsa-mir-145_TGFB2 | 1.76e-3 | 7.78e-1 | 1.37e-1 | 1.27e-1 | 1.37e-1 |
AL139423.1_hsa-mir-424_TSC22D2 | 4.28e-3 | 4.10e-4 | 5.25e-4 | 9.49e-2 | 5.25e-4 | ||
AL139423.1_hsa-mir-454_SOX4 | 7.60e-3 | 9.14e-1 | 3.13e-4 | 8.16e-1 | 3.13e-4 | ||
2 | AL139423.1_hsa-mir-150_HILPDA | 1.81e-7 | 4.36e-1 | 5.72e-1 | 2.91e-1 | 5.72e-1 | |
AL139423.1_hsa-mir-122_SLC2A3 | 1.32e-5 | 3.76e-3 | 6.84e-2 | 7.66e-1 | 6.84e-2 | ||
AL139423.1_hsa-mir-195_PAFAH1B2 | 1.24e-4 | 3.57e-1 | 1.00e-2 | 3.01e-1 | 1.00e-2 | ||
LUAD | 1 | AC123768.4_hsa-mir-301b_ENPP5 | 4.91e-5 | 6.41e-1 | 3.50e-1 | 7.09e-1 | 3.50e-1 |
MZF1-AS1_hsa-mir-665_DNALI1 | 1.27e-3 | 3.53e-1 | 1.81e-1 | 8.39e-1 | 1.81e-1 | ||
AGAP11_hsa-mir-424_CPEB3 | 1.48e-3 | 6.02e-2 | 1.23e-1 | 9.62e-1 | 1.23e-1 | ||
2 | SOX2-OT_hsa-mir-301b_ENPP5 | 7.17e-5 | 6.21e-1 | 7.73e-1 | 7.09e-1 | 5.28e-1 | |
AC234582.1_hsa-mir-665_DNALI1 | 1.37e-4 | 8.78e-1 | 8.00e-1 | 9.42e-1 | 9.17e-1 | ||
AC004832.1_hsa-mir-17_ENPP5 | 4.47e-3 | 4.05e-3 | 1.33e-1 | 8.48e-1 | 1.33e-1 | ||