Fig. 5
From: ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer
Biological characteristics and different immune statuses of risk models. A-C GSEA analysis for Top5 biological characteristics of GO (A), KEGG (B) and REACTOME (C) between high- and low-risk groups. D-E Histograms of relative abundance of 22 immune cells analyzed by the CIBERSORT algorithm in the training set (D), and box plots of immune cell infiltration enrichment analysis in the low-risk group (yellow box) and high-risk group (green box) (E). F Correlation analysis of PBX1, IGHM and CXCL13 genes with immune cells. G Scatter plot of correlation between IGHM gene expression levels and NK_cells_resting cells. H Correlation scatter plot of CXCL13 gene expression level with T_cells_follicular_helper cells. GSEA, Gene Set Enrichment Analysis; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes. *p < 0.05, **p < 0.01, ***p < 0.001, and “ns” represents non-significant