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Table 3 Subgroup-specific association between METTL4 polymorphism s and the risk of severe pneumonia

From: Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China

    

Primary pneumonia

Secondary pneumonia

CHR

BP

dbSNP

Minor Allele

MAF

OR(95%CI)

p -value

MAF

OR(95%CI)

p -value

18

2561851

rs12457106

A

0.07

0.76(0.61–0.94)

0.0110

0.10

1.16(0.88–1.55)

0.2929

18

2542078

rs72857010

C

0.06

1.08(0.85–1.37)

0.5071

0.05

1.31(0.93–1.83)

0.1217

18

2559434

rs9989554

C

0.30

1.18(1.04–1.33)

0.0083

0.32

1.29(1.07–1.54)

0.0061

18

2575199

rs80010836

C

0.16

1.16(1.00–1.35)

0.0532

0.17

1.30(1.04–1.63)

0.0237

18

2537639

rs17534687

A

0.14

1.10(0.94–1.28)

0.2501

0.15

1.23(0.97–1.55)

0.0837

18

2557926

rs9948895

G

0.36

1.06(0.95–1.19)

0.2841

0.38

1.15(0.97–1.37)

0.1153

18

2554836

rs16943442

G

0.16

1.20(1.03–1.39)

0.0181

0.17

1.30(1.04–1.63)

0.0236

18

2538788

rs11663148

T

0.20

0.97(0.84–1.11)

0.6172

0.21

1.02(0.83–1.24)

0.8840

18

2560519

rs2138848

C

0.34

1.12(1.00–1.26)

0.0603

0.35

1.16(0.97–1.39)

0.0978

18

2551772

rs66873847

A

0.11

1.08(0.91–1.29)

0.3743

0.10

1.06(0.80–1.39)

0.6963

18

2548845

rs2644175

G

0.19

1.04(0.90–1.20)

0.5830

0.18

1.03(0.83–1.27)

0.8212

  1. Abbreviations: CHR chromosome, BP base pair (where the SNP is located), SNP single-nucleotide polymorphism, MAF minor allele frequency in patients, OR odds ratio, CI Confidence interval
  2. P-values were adjusted by gender and age. Calculation of the OR was also based on the risk allele of each SNP